Nate, a 19 year old film student, and Margaret, a 52 year old spinster, are best friends in an odd, quirky, totally working kind of way... until Nate's audacious classmate Darla sets him up on a date with James. Nate's new life shakes apart his friendship with Margaret, who goes off on her own to start a career as a stand-up comedian.
Brooke (Bonnie Dennison) is devastated that she's pulled out of her high school so her family can move to a new town. Even worse, her stepmother is pregnant with a new addition to her dysfunctional family. All seems lost until she becomes smitten with a charming guy (Michael Welch). He's gorgeous, sweet, thrilling, everything her life isn't...until he reveals a menacing dark side.
In this '60s retro prequel to the bizarro-noir Bloodsucker's Handbook (AKA Enchiridion), Bloodsucker's Planet follows the crew of the space ship Argosy as they respond to a distress signal from the industrial Planet Mara only to discover the planet is ruled by the sinister Mother Vampire. Along the way, they encounter disease-carrying Mara bats, a talking space roach, and Adrianna, the gynoid whose developing self-awareness is aided by her collection of vintage romance comics.